345 research outputs found

    Andrew Gregg Curtain\u27s Signature

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    This signature of Andrew Gregg Curtin is clipped from a larger page. Curtain served as the Governor of Pennsylvania during the Civil War, helped defend his state during the Gettysburg Campaign, and led organization of the creation of the National Cemetery and the ceremony that included Abraham Lincoln\u27s Gettysburg Address.https://scholarsjunction.msstate.edu/fvw-manuscripts-original-manuscripts/1227/thumbnail.jp

    20 year anniversary of the Tampere Programme: Europeanisation Dynamics of the EU area of Freedom, Security and Justice. CEPS Research Paper 12 May 2020.

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    The end of 2019 coincided with the 20 anniversary of the Tampere European Council Conclusions of October 1999 (The Tampere Programme). The Programme set for the first time in European integration a common policy programme on Justice and Home Affairs. It also corresponded with the 10 year anniversary of the Lisbon Treaty which brought a majority of these policies under the Community method of cooperation and enshrined a legally binding EU Charter of Fundamental Rights. This collaborative Book examines and takes stock of the main policy and legislative developments during the last 20 years of EU cooperation on the Area of Freedom, Security and Justice (AFSJ). The Chapters review the current facets and latest steps in all relevant AFSJ policy domains, including migration, borders, asylum and criminal justice and police cooperation. They critically assess the main achievements, unfinished components, as well as the new and old challenges, paying attention to different types of ‘Europeanization’ dynamics (narratives, actors and instruments), and their relations and compliance with EU rule of law, democratic and fundamental rights values. The Volume is based on the contributions delivered in a Conference co-organised by CEPS, the Migration Policy Centre (MPC) and the Law Department of the European University Institute (EUI), in cooperation with the Finnish Permanent Representation to the EU on 3 and 4 October 2019 in Brussels. The Conference was an official event part of Finland’s Presidency calendar which ran during the second half of 2019

    Acute alcohol administration dampens central extended amygdala reactivity.

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    Alcohol use is common, imposes a staggering burden on public health, and often resists treatment. The central extended amygdala (EAc)-including the bed nucleus of the stria terminalis (BST) and the central nucleus of the amygdala (Ce)-plays a key role in prominent neuroscientific models of alcohol drinking, but the relevance of these regions to acute alcohol consumption in humans remains poorly understood. Using a single-blind, randomized-groups design, multiband fMRI data were acquired from 49 social drinkers while they performed a well-established emotional faces paradigm after consuming either alcohol or placebo. Relative to placebo, alcohol significantly dampened reactivity to emotional faces in the BST. To rigorously assess potential regional differences in activation, data were extracted from unbiased, anatomically predefined regions of interest. Analyses revealed similar levels of dampening in the BST and Ce. In short, alcohol transiently reduces reactivity to emotional faces and it does so similarly across the two major divisions of the human EAc. These observations reinforce the translational relevance of addiction models derived from preclinical work in rodents and provide new insights into the neural systems most relevant to the consumption of alcohol and to the initial development of alcohol abuse in humans

    Intra-Rater & Inter-Rater Reliability In 2nd Year DPT Students Performing The Navicular Drop Test

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    The Navicular Drop Test (NDT) is used as a clinical measure of mid-foot pronation. Objective measurements are rooted in the trust of the tool. When utilizing the NDT, the tool is the practicing clinician. Research has revealed that experienced clinicians have good-excellent intra- and inter-rater reliability when measuring navicular drop (ND). Current data reports ~25,000 practicing US PTs have \u3c 3 years experience. There is limited research exploring the intra- and inter-rater reliability of less experienced DPTs when performing the NDT. The purpose of this research report was to determine the intra- and inter-rater reliability of three 2nd year DPT students.https://dune.une.edu/pt_studrrposter/1003/thumbnail.jp

    Possession (1)

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    A co-curated exhibition of 20 artists from the UK, Thailand, USA, France, Cambodia, Vietnam and Switzerland, co-funded by Arts Council England and the Bangkok Art and Cultural Centre (BACC). Possession (1) ran at Bangkok Arts and Culture Centre from 14 March-26 May, 2013 (extended from the original end date by 3 weeks) and was co-curated by Dutton and Dr Brian Curtin of Bangkok University. They had previously co-curated Unspeaking Engagements (2009-10) which exhibited the work of 13 international artists at Chulalongkorn Art Center in Bangkok. Unspeaking Engagements led to the recognition – from which Possession (1) emerged – that an understanding of appropriation in art practice was by no means universal. Dutton’s previous curatorial projects were informed by his interests in ‘occupying’ the rhetorical structures of power (see output 4) and in a critical interest in the teleological aspects and fetishes of contemporary art, both of which are evident in Possesion (1)

    Metabolic Tumor Profiling with pH, Oxygen, and Glucose Chemosensors on a Quantum Dot Scaffold

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    Acidity, hypoxia, and glucose levels characterize the tumor microenvironment rendering pH, pO2, and pGlucose, respectively, important indicators of tumor health. To this end, understanding how these parameters change can be a powerful tool for the development of novel and effective therapeutics. We have designed optical chemosensors that feature a quantum dot and an analyte-responsive dye. These noninvasive chemosensors permit pH, oxygen, and glucose to be monitored dynamically within the tumor microenvironment by using multiphoton imaging.National Cancer Institute (U.S.) (Grant R01-CA126642
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